Guide & Use Cases
Everything you can do with InTree - input patterns, search modes, filters, and real-world use cases. Click any example to try it live.
Three search modes
Explore
1+ entitiesEnter one entity — or combine several into a single graph. Choose which lenses to surface (drugs, diseases, biomarkers, pathways, behaviours, interventions…) and get a living knowledge graph you can grow: verify a link, trace a pathway, expand a node, or add your own — all without leaving the map. Plus novel connections, mechanisms, research gaps, and candidate pathways.
Verify
2 entitiesGet every piece of evidence classified as SUPPORTS, CLAIMED, CONTRADICTS, or INDIRECT. See study quality breakdown, a weighted verdict, and paper metadata with DOI links.
Trace Pathway
3+ stepsBuild a pathway chain with any mix of drugs, genes, diseases, or biological processes. Each hop is verified against curated databases and 240M+ papers - scored, directionally labeled, and mechanistically explained. Use auto-find to discover intermediates between two endpoints.
Your Explore graph is a workspace
Explore doesn't just draw a picture — it's an interactive map you build on. Verify and Trace happen right on the graph, and every finding merges back in, so one graph grows into your whole answer.
Click any node — a toolbox opens
Expand its connections, Verify its link to another entity, Trace a pathway from it, or read the Evidence behind it. Verify and Trace run in place — no page switch — and the result is added to the same graph.
Grow the graph, in context
Add any node and (by default) InTree also finds how it connects to what's already on your map — so a new entity draws itself into the picture instead of floating alone.
Click a faint line to identify it
Grey hairlines are co-mention leads. Click one (or a node) and InTree types the relationship — direction, effect, and evidence — turning a lead into a labeled edge that sticks.
Mechanisms & Pathways
Run it on any pair to surface multi-step routes between entities — each hop scored, directionally labeled, and grounded in curated databases + the literature.
Graph Insights & novel leads
A side panel ranks the graph's connectors, research gaps, and clinical links, and surfaces low-evidence novel leads worth a closer look.
Declutter & focus
Toggle Weak / Strong / All edges, filter by category or relationship type, search the Edges list, or erase and keep-only — then send the graph to a Board, export a PNG, or share a link.
What you can type
Natural language questions
How each mode's input works
Relationship types (optional)
These power the lens in Explore, the relationship selector in Verify, and each hop in Trace. Leave them on the default to include every relationship type.
What every result gives you
Not a list of papers to read - a structured view of what the evidence actually says.
Evidence you can act on
Every item classified so you know what you're reading before you open the paper.
- SUPPORTS / CLAIMED / CONTRADICTS / INDIRECT - all surfaced, not just supporting
- • Study type on every paper: RCT, Review, Clinical, or Preclinical - changes how much weight you give it
- • Citation count and DOI - trace back to the source in one click
- • Weighted verdict: Strong support / Contested / No clear consensus
The full picture, not a slice
Lenses that surface what keyword search buries.
- Contested - shows both sides simultaneously; supporting and contradicting papers side by side
- Recent - last 3 years only, for fast-moving fields
- High impact - 10+ citations; the evidence that shaped the field
- • Interactive knowledge graph of every related entity for your query
Insights you can share
From a quick snapshot to a shareable evidence package.
- • Evidence distribution chart - see consensus vs. conflict at a glance
- • Publication trend by year - emerging topic or decades-established?
- • Study type breakdown - how much comes from RCTs vs. preclinical?
- • Clinical trial data for drug-disease pairs - phase, active status, NCT links
- Export to CSV
- Permanent share link
- Save to Project
Save & organize — Projects and Boards
Your work doesn't disappear when you close a tab. A Project holds everything for one line of research; a Board is where you assemble and annotate the graphs you've built.
Projects
One workspace per topic — everything you save stays scoped to it and separate from your other work.
- Save papers & searches as you go — build up an evidence base for the project
- Knowledge Map — turn the project's saved papers & uploads into one expert-grade graph, with mechanisms, gaps and synthesis
- Alerts & notifications when new evidence matches the project
- All of the project's Boards live here too
Boards
Any graph → Send to board to get an editable, decoupled copy you can arrange freely.
- Combine several graphs as layers on one canvas — compare or merge them
- Draw and annotate over the top — notes, arrows, highlights
- Filter, focus, and rearrange nodes; add nodes right on the board
- Export as PNG or share a read-only link